Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

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Original data

TitleFirst AuthorYearLink to paperBipolars numberControls, number ofDiagnosisMethodCT basedAge Bipolarssd age bp ttxSD Age Bipolarsage cntrl ttxAge ControlsSD Age ControlsFemale BPsFemale CtrlsBipolars numbers included in meta-analysisControls, numbers included in meta-analysisBipolar (left)Bipolar SD (left)Control (left)Control SD (left)Bipolar (right)Bipolar SD (right)Controls (right)Controls SD (right)BipolarsBipolars SDControlsControls SD
Structural brain abnormalities in first-episode maniaStrakowski SM (B)1993http://dx.doi.org/10.1016/0006-3223(93)90098-X1716DSM-III-RMRI028.46.830.97.310917165.90.95.50.7
Aylward EH (Females)1994http://ajp.psychiatryonline.org/cgi/reprint/151/5/6871413DSM-III-RMRI040.710.438.89.2141314134042.7987.64375974.3
Aylward EH (Males)1994http://ajp.psychiatryonline.org/cgi/reprint/151/5/6871617DSM-III-RMRI037.911.936.790016174625.41008.53780.7916.2
Dupont RM (A)1995See Sept 1995 p747, Archives of General Psychiatry3626DSM-III-RMRI036.610.839.19.4121136261808.81259.721806.35243.73
Sax KW1999Jan 1999 p139 American Journal of Psychiatry (OVID)1712DSM-III-RMRI027627574171291.49.40.9
Getz GE2002http://dx.doi.org/10.1016/S0920-9964(01)00210-91212DSM-IVMRI029.28.730.77.5431212nsnsnsnsnsnsnsns11.71.89.91.3
Strakowski SM2002http://ajp.psychiatryonline.org/cgi/content/full/159/11/18411832DSM-IVMRI0226246716181612.41.5121.3
Strakowski SM2002http://ajp.psychiatryonline.org/cgi/content/full/159/11/18411732DSM-IVMRI02562461116171611.81.5121.3
Beyer JL (A)2004Wiley InterScience: Journal: Abstract3635DSM-IVMRI058.87.9163.25.35242236353.650.63.860.483.90.754.140.547.541.2680.93
DelBello MP2004Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder - Bipolar Disorders, Vol 6, Issue 1, pp. 43-52 (Full Text)2320DSM-IVMRI016.32.417.21.999232060.85.90.76.20.96.10.812.21.712.11.4
Chang K (A)2005http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0890-8567&volume=44&issue=6&spage=5652020DSM-IVMRI014.62.814.12.84420204.670.464.560.724.830.454.820.659.510.819.381.33
Ahn MS2007http://dx.doi.org/10.1016/j.jad.2007.04.0154622DSM-IVMRI011.32.711.12.7201046228.340.978.560.9

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Strakowski SM (B) 1993 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Aylward EH (Females) 1994 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Aylward EH (Males) 1994 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Dupont RM (A) 1995 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Sax KW 1999 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Getz GE 2002 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Strakowski SM 2002 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Strakowski SM 2002 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Beyer JL (A) 2004 nan nan nan nan nan 0.540000 nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
DelBello MP 2004 nan nan nan nan nan 0.800000 nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Chang K (A) 2005 nan nan nan nan nan 0.650000 nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Ahn MS 2007 nan nan nan nan nan nan nan nannan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Meta-analysis (fixed effect) 0 0 0.000 inf -inf inf 0.000 1.000 100%
Meta-analysis (random effects, DSL) nan inf nan  nan nan nan 100%
σa: 0.000000 Q: 0.000000 dof: -1.0 P-value: nan

Forest plot

Funnel plot

Effect size Standard error -0.50 -1.00 -1.50 -2.00 0.50 1.00 1.50 2.00 0.30 0.60 0.90 1.20

Warning

Column not matched "number_of_experimentals". Column not matched "number_of_controls". Column not matched "number_of_experimental_events". Column not matched "number_of_control_events". Column not matched "mean_experimentals". Column not matched "mean_controls". Column not matched "sd_experimentals". %d format: a number is required, not numpy.float64

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.